You don't give almost any details other than "what's best to make ammo fast", especially with regards to caliber and your budget.
The fastest answer to the fast/best question is going to be a Dillon XL750 or a Dillon 1050. But either way, you're talking about a fat outlay of cash.
There's just not much conversation without a lot more information. And as was said in post #2, nobody can really get primers for anything less than FIVE times previous retail (and TEN times at some guns shows) and powder is almost but not quite as difficult right now.
I like to swap brass... and I'm looking for .32 H&R Mag, .327 Fed Mag, .380 Auto and 10mm. If you have some and would like to swap for something else, send me a note!